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As broad-spectrum neutral and cationic amino acid transporters such as SLC6A14, SLC7A7 or SLC7A1 can be induced to be expressed in immune microenvironment to mediate arginine uptake during DCs activation

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Abstract Many local and systemic diseases especially diseases that are leading causes of death globally like chronic obstructive pulmonary disease, atherosclerosis with ischemic heart disease and stroke, cancer and severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) causing coronavirus disease 19 (COVID-19), involve both, (1) oxidative stress with excessive production of reactive oxygen species (ROS) that lower glutathione (GSH) levels, and (2) inflammation

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